Invitrogen IL-22 Monoclonal Antibody (1H8PWSR), PerCP-eFluor 710, 100 µg, eBioscience™
On demandInvitrogen IL-22 Monoclonal Antibody (1H8PWSR), PerCP-eFluor 710, 100 µg, eBioscience™
The 1H8PWSR monoclonal antibody reacts with mouse interleukin(IL)-22. IL-22 is a 20 kDa member of the IL-10 cytokine family that is secreted primarily by Th17, NK cells, and some other T cells. In in vitro Th17 cultures, induction of IL-22 expression is greater in response to IL-23 than IL-6 or TGF-β, suggesting that this cytokine may be secreted by more fully differentiated Th17 cells in vivo. A heterodimer consisting of IL-10R2 and IL-22R1 serves as the receptor for IL-22. Th17-secreted IL-22 binds to the IL-22 receptor complexon target cells to induce the expression of anti-microbial peptides β-defensin-2 and β-defensin-3. Recently, it was demonstrated that IL-22 is able to protect hosts against bacterial infections of the lungs and gut.
PerCP-eFluor® 710 can be used in place of PE-Cy5, PE-Cy5.5 or PerCP-Cy5.5. PerCP-eFluor® 710 emits at 710 nm and is excited with the blue laser (488 nm). Please make sure that your instrument is capable of detecting this fluorochrome. For a filter configuration, we recommend using the 685 LP dichroic mirror and 710/40 band pass filter, however the 695/40 band pass filter is an acceptable alternative.
Our testing indicates that PerCP-eFluor® 710 conjugated antibodies are stable when stained samples are exposed to freshly prepared 2% formaldehyde overnight at 4°C, but please evaluate for alternative fixation protocols.
Features
- Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser.
- Filtration: 0.2 µm post-manufacturing filtered.
- Recommended Isotype Control: Rat IgG1 kappa Isotype Control (eBRG1), PerCP-eFluor 710, eBioscience™.
There are no specifications
There are no report
You May Also Like
Invitrogen EOMES Monoclonal Antibody (Dan11mag), PerCP-eFluor 710, 25 µg, eBioscience™
$ On demand
On demand
Invitrogen Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Functional Grade, 50 mg, eBioscience™
$ On demand
On demand
Invitrogen CD4 Monoclonal Antibody (GK1.5), NovaFluor Yellow 570, 25 µg, eBioscience™
$ On demand
On demand
Invitrogen 50 µg CD45R (B220) Monoclonal Antibody (RA3-6B2), Biotin, eBioscience™
$ On demand
On demand
Invitrogen CD11c Monoclonal Antibody (N418), APC-eFluor 780, 100 µg, eBioscience™
$ On demand
On demand
Invitrogen CD4 Monoclonal Antibody (SK3 (SK-3)), NovaFluor Yellow 700, 25 Tests, eBioscience™
$ On demand
On demand
Invitrogen CD107a (LAMP-1) Monoclonal Antibody (eBioH4A3), FITC, 25 Tests, eBioscience™
$ On demand