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MSI Microsatellite instabilit, (PCR)

On demand
Order number : ON-P10
(Ex-work price)
$ On demand

BAT-25, BAT-26, NR-21, NR-24,MONO-27, Penta C and Penta D allelic profiles 


Main indication:

CRC.


Test usage:

MSI is particularly associated with colorectal cancer, where 15-20% of sporadic tumors show MSI, in contrast to the more common chromosomal instability (CIN) phenotype, with MSI status being an independent prognostic indicator. MSI analysis is also clinically useful in identifying patients at increased risk of hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch Syndrome, where a germline mutation of a MMR gene causes a familial predisposition to colorectal cancer.

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